Rebirth of the God-level Xueba

At lunch time, Grace came to Yang Rui with a plate, sat down, and asked, "Is there no one here.

"No, welcome, Miss Grace." Huang Mao, who was at the same table, got up quickly and said, "I happen to have something to do..."

"Sit down, I want to have a chat with you." Grace sat down Huang Mao with her eyes.

Huang Mao was inexplicably affected, and obediently returned to the position just now.

Tu Xian and Wang Xiaoyun, who originally wanted to leave, also looked at Grace curiously.

"I want to join your experimental group, can I?" Grace didn't have any foreplay at all, and directly inserted into Yang Rui, just like her previous style.

Yang Rui put down his chopsticks in surprise, and said, "You mean Huarui Laboratory?"

"correct."

"I'm afraid I can't afford your salary, and Huarui Laboratory can't afford too much research funding." Yang Rui thought for a while and said slowly.

Although Grace often works for nonprofits, she is also a professor at Cambridge, and she earns more than $30,000 a year in either job.

In fact, professors at the University of Cambridge earn more than $100,000 if they teach both departments and colleges.

However, Huarui Laboratory currently does not recruit foreign researchers, and simply pays Grace a salary of tens of thousands of dollars, which Yang Rui thinks is not very appropriate.

The most important thing is that Huarui Lab can't afford the joining of scholars like Grace for the time being.

Put the salary aside first, after any laboratory recruits a talented person. The first thing to come out should be research funding.

Yang Rui is not very clear about Grace's ability, but it is the general level of Cambridge professors. It is normal to spend millions of dollars a year on experiments.

If it is an ion channel laboratory, spending millions of dollars a year to recruit a Cambridge professor waiting to win an award is barely reasonable, but Huarui Laboratory is not a real non-profit laboratory, and a scholar with a special personality like Grace joins. Yang Rui felt that he couldn't suppress it.

Grace naturally thought about such a problem. He said: "How much annual salary can you afford? I can take the same salary as Chinese scholars and accompany you to complete the deferiprone project. How about it?"

As soon as Grace said this, Yang Rui was so shocked that he couldn't hold his chopsticks steady: "You don't want research funding?"

"I just want to help you quickly make deferiprone. As long as I can use deferiprone research funds during the deferiprone project to conduct related research."

"The current salary in China is very low, only more than a hundred dollars a month." Yang Rui is not trying to scare Grace, Huang Mao and others currently have the highest salary in the laboratory. That is only more than 1,000 yuan, and the full overtime pay is 3,000 yuan at most, converted into US dollars. Usually it is less than 500. Of course, the official price is more than that, but normal people cannot exchange the official price for dollars.

Grace had thought of this earlier, and said calmly: "I can live with savings. My life is not demanding."

"I trust you, but..."

"Salary is not a problem." Grace said: "I just hope that deferiprone will be available soon, I believe. With your ability, it will be done."

Grace feels very good about Yang Rui.

She felt that Yang Rui was the purest researcher she had ever met.

Developing new drugs is not an easy task, and it is never cheap. The average development cost of $100 million for the whole process, or the half-stage development cost of $10 million, are beyond normal philanthropic behavior.

Grace hadn't heard of any philanthropist, or charitable organization, who would spend all of his fortune developing a drug for a disease that didn't make money.

All drug development projects are led by pharmaceutical companies based on profits. Even for charitable organizations established for certain diseases, all they can do is urge and negotiate, and they are powerless to lead drug development.

Yang Rui, as an important member of Sinovel, personally carried out this work, which can be understood as his excellent technical level, and also as the full-fledged person in charge of this project.

Grace couldn't imagine how many quarrels and arguments, and how powerful persuasion skills would be needed for Yang Rui to get Sinovel to resolutely invest in the research of deferiprone.

No matter what it is, Grace admires it.

Yang Rui didn't know what Grace was thinking, so after thinking about it, he said, "I can't guarantee anything..."

"I don't need your guarantee..."

"I can't guarantee that deferiprone will go on the market, nor can I guarantee what step deferiprone can achieve. I also can't guarantee the price of deferiprone after it goes on the market, or even whether deferiprone can continue to be completed in our hands. You Do you understand? This is a very risky project, and it still belongs to the capital in the end." Yang Rui said it very carefully and practically. He has the ability to complete preclinical research at a relatively low cost, which accounts for more than one-third of new drug research, but for capital, this is only the first step in the long march.

Not to mention the clinical phase I and clinical phase II, which prevent 90% of drugs from being launched, just the extremely high cost of clinical phase III can block the ambitions of any small pharmaceutical company. Each clinical phase III trial can range from two to three hundred to as many as 1,000 people. After eight or nine trials, the cost can easily reach hundreds of millions of dollars. Even so, the FDA may not be able to pass the review.

And outside the United States, the cost of clinical trials will not be low, and the cost of public relations may be even higher...

The development of new drugs is a bottomless pit. Yang Rui's participation in it now can be called ambitious. The whole process of developing such a thing is simply beyond his capabilities.

The future of deferiprone can only be sold to large pharmaceutical companies after better data are obtained, just like the scientific research process of all small pharmaceutical companies.

This is the operating rule of the pharmaceutical system. Small biotechnology companies conduct research on one or two targets and do preclinical research. Large biotechnology companies conduct research on multiple targets and still do preclinical research. Small pharmaceutical companies While doing research on biological targets, the company acquires the target research of biotechnology companies, and conducts preliminary compound synthesis and even clinical research. .

In European and American countries, such a system is unbreakable, and only excellent capital can change the operating posture. In addition, no matter how strong a scholar is, he can only participate in the film like a well-known director in the Hollywood system, but cannot lead the film. Biotechnology companies can only produce films like film production companies, but cannot distribute films. Only large pharmaceutical companies have the ability to operate and make all-round profits, just like large Hollywood distribution companies.

Grace pondered for a few seconds, then said again: "I believe in you."

Yang Rui was surprised and couldn't help asking: "Why do you believe me?"

"With your ability, if you want to make money, you can choose other drugs, but you chose deferiprone." Grace smiled slightly and said, "As I said, you are an excellent scholar, but you First and foremost a fighter..."

"Fighter, it's really out of the question."

"Maybe you don't know, but you are indeed launching an assault on this decadent medical system. You may fail, most of them will fail. With your intelligence, you probably expected it, but you still stood up and ran away. It sounds like Don Quixote." Grace's voice was not high enough that only her deskmate could barely hear her.

Yang Rui raised his head, and suddenly, he was a little uncertain about his thoughts. Perhaps, there was really some element in his subconscious, which was restlessness and uneasiness.

However, after a few seconds, Yang Rui let go of this idea and said: "Our goal is to make deferiprone and complete relevant research as much as possible, that's all."

"I understand, so, did I join?" Grace said I believe in your expression, and stared straight at Yang Rui.

Yang Rui hesitated for a moment, then said, "Aside from your salary, you won't get any benefits."

"I would."

"Okay, we should also enter the stage of animal experiments, are you willing to do it?"

"Animal experiments? I'm the best at this." Grace noticed Yang Rui's expression, smiled, and said, "Don't worry, I'm not a hypocritical environmentalist."

...