Rebirth of the God-level Xueba

Chapter 754 Thalassemia

With the arrival of Tian Bing, the number of people in the ion channel laboratory expanded rapidly.

In one week, Yang Rui dug up three calves, namely Tian Bing and Jiao Yangping from Tsinghua University, and Wang Sisheng from Beili.

Among them, Jiao Yangping is the future bull who will become an academician. He is very powerful. This can be said to be the pinnacle of Chinese scholars. If you look at the number of Chinese academicians for 30 years, the number is still quite small, even less for biology majors.

And Wang Sisheng from Bili has no experience of studying abroad or giving lectures, but he can still reach the level of the Thousand Talents Plan, which is also a relatively big calf.

Because of this, Yang Rui quickly started the research on genome and cloning.

Not only Yang Rui, Xu Zhengping, Professor Cai, Dean Liu and others were also scratching their heads in excitement.

They didn't expect to catch a talented person who would become an academician or Changjiang scholar in the future, but in this period of time, domestic first-class scholars themselves are scarce.

Only when a large number of scholars trained by U.S. imperialism return to China can the number of first-class domestic scholars barely exceed the number of giant pandas in the same period.

In terms of a certain professional field alone, the giant panda still wins.

The three people brought by Yang Rui are now the backbone of Tsinghua University and Beijing University, so they are naturally the backbone of Peking University. They can be placed in any school other than Tsinghua University and Peking University. Before the professor sequence 5%, it is the object that all schools will win over. Even at Peking University, Tian Bing, Jiao Yangping, and Wang Sisheng are also high-level scholars, and it is worth spending a lot of effort to win them over.

Of course, the Mavericks are Mavericks after all, and they haven't reached the level of wooing regardless of cost. Professor Cai and Dean Liu are very happy that Yang Rui can do it, but it's not necessarily necessary for them to do it themselves.

What's more, there must be a certain opportunity to pull people.

It should be said that the publication of "Genomics" and the publicity of "Chicago Reading News" gave scholars who switched to the ion channel laboratory sufficient reasons to switch jobs.

In this day and age, transferring jobs because of money is a reason that can only be said in private. In the public market, this is a very immoral act, and the university academic circle is destined to be a small circle. Reasons are only used by young scholars who are in a hurry.

After reaching Tian Bing's age and prestige, the reason why he can change jobs is either that he failed to negotiate with his old club, or he can only go for lofty ideals and the pursuit of knowledge.

Nowadays, going to the author of "Genomics" can be regarded as the pursuit of knowledge.

Tian Bing was like this, Jiao Yangping was like this, and so was Wang Sisheng.

The work in the ion channel laboratory has also become easier. Counting the former Su Xiankai, Fan Zhenlong, and Xu Zhengping, there are already six researchers under Yang Rui, which is basically the same size as the Huarui laboratory.

These are real researchers who have been trained after many years of scientific research. Yang Rui watched the laboratory for a few days and was basically relieved.

Among the three newcomers, Tian Bing and Jiao Yangping are both thorough academics. Yang Rui is familiar with the experimental methods and the way of filling out the report. , I am familiar with the working methods of the ion channel laboratory.

After a week of this, Yang Rui recruited two more dogs from the applicants—the salary was comparable to that of Su Fan from Beiyan Agricultural College, and the recruitment work was over.

If more people are recruited, the ion channel laboratory will not be able to accommodate it.

In fact, at this level, the workload of a laboratory is already quite large.

The trio even brought a lot of jobs—or benefits, from their previous units.

Going to work on Monday, Yang Rui saw a letter on the laboratory table as soon as he arrived at the laboratory.

Wang Sisheng put down the test tube and walked over with a smile, "Mr. Yang, the invitation I received earlier was a conference organized by Peking Union Medical College Hospital and several universities and research institutes.

It is nationwide, and there are exactly three places. I would like to invite you to go with Professor Xu Zhengping. Do you think it is suitable? "

Wang Sisheng is the youngest of the three new arrivals. He is about thirty-six or seventeen years old. He still looks a little pink. If he doesn't know it, he thinks he is a fresh graduate. Of course, at his age, he is placed abroad, that is, he has just graduated from Phd.

Wang Sisheng brought out good things as gifts, Yang Rui also intended to win over, and immediately said: "Okay, one day, you call Xu Zhengping, let's go and have a look together."

"The day after tomorrow is the pre-meeting, which is also the deadline for submitting articles, and then the meeting will be held in two days, and the place will be chosen at Xiehe Hospital. Didn't they have a cooperation with the World Health Organization two years ago? It's called the World Health Organization's Classification of Diseases." Center, where the meeting will be held, staying at the guest house of Xiehe Hospital, and there is a full buffet, and it is said that there is also Western food." Wang Sisheng's focus is naturally on the back, he showed the invitation letter in his hand, and said with a smile: "The three of us Take a formal invitation letter to go in, you can eat a buffet, and there are three vice-joints, one can bring someone in to listen to the lecture, but you can't speak, and you can't eat the buffet, you see, who is better for the vice-joint?"

"You can discuss it with Lao Xu." Yang Rui didn't care about this kind of thing, but said curiously: "The guest house of Xiehe Hospital also has a buffet now?"

"Isn't this popular? They definitely can't open business like Huarui Gymnasium, and they can't make money back. However, they do it from time to time internally, and everyone likes it very much." Wang Sisheng licked his lips with a smile, with some aftertaste mean.

Yang Rui smiled and said, "You seem to go often."

"How can it be, you have to be invited to go. As for Beijing Xiehe this time, it was also an invitation coupon given by a friend."

"So popular?"

"If you want to go, you must go casually, I almost did." Wang Sisheng shook his head with a smile, and said: "Nowadays, people only recognize professors, and it's worthless to bring a deputy in front."

"Write a few articles and you will be a professor. Don't worry." Yang Rui patted Wang Sisheng on the shoulder to comfort him.

Wang Sisheng smiled helplessly. He did make the choice after seeing the speed of the results of the ion channel laboratory. Otherwise, it would be much more difficult to compete for a professor at Peking University than at BIT.

Three days passed in a flash.

Yang Rui, Wang Sisheng and Xu Zhengping, together with Zhao Pingchuan and other three scientific researchers, boarded two cars from Zeneca and went to the World Health Organization Classification of Diseases Center of Union Medical College Hospital.

Zhao Pingchuan originally worked in Tang's concentrated laboratory, and was assigned to Yang Rui's scientific research group for a long time. After Yang Rui's ion channel laboratory was established, he still came to find Zhao Pingchuan frequently. After a long time, Zhao Pingchuan simply obtained the consent of Tang Zhong and transferred to the ion channel laboratory.

Unlike Yang Rui's recently recruited head dogs with establishments, Zhao Pingchuan is just an ordinary Peking University student. He has no consideration for establishments and other aspects, and he can change places if he wants to.

Moreover, compared with Tang Ji's follow-through, the large number of projects in Yang Rui's ion channel laboratory can make better use of Zhao Pingchuan's mathematical ability. The author column is signed.

"The venue of Xiehe Hospital is here." The driver of the car stopped the car steadily, got out of the car quickly, and opened the door for Yang Rui and others as if welcoming foreign guests.

"Mr. Yang Rui!" The scholar guarding the door, wearing a white coat, looked over because of his shiny dash, but let out a cry of surprise.

"Hello." Yang Rui looked at the other party with a confused face.

"I've seen your photos, and the news on TV." The white coat revealed the reason in one sentence, bent over to shake hands with Yang Rui, and said with a smile: "Director Yang can come to our Xiehe, and we will be full of glory and glory. Shenghui, Director Yang, this way please."

While introducing himself in the white coat, he led Yang Rui on a 300-meter walk to the conference hall.

Wang Sisheng's eyes glared brightly. He sat down and gave Yang Rui a thumbs up, saying, "Director Yang is famous and powerful."

"Have you read martial arts books recently?" Yang Rui interrupted with a smile. Naturally, he is well-known. Both "Cell" and "Nature" are top journals in the world. Those who can publish articles on these journals may not have a few articles even if they are tied up in hospitals across the country. Although the main job of a doctor is not necessarily to publish articles, publishing articles and producing results is still the most dazzling job. However, Yang Rui did not come here to show off, so he simply switched the direction of his speech to chat mode.

Except for a few people who came to say hello, generally speaking, Yang Rui had a pleasant chat.

The good mood lasted until the middle of the meeting. When many pictures of patients began to be displayed in the meeting place, Yang Rui's expression became serious.

The enlarged photos of the patients come from many children and teenagers with deformed bodies, distorted abdomens, slender legs, and deformed heads.

"Globinogenic anemia is a genetic disease that has been discovered in my country in recent years. It is especially common in Guangdong, Guangxi and central Sichuan. The treatment of intermediate and severe thalassemia is very difficult and requires long-term blood transfusions. treatment, and the complications caused by long-term blood transfusion have further increased the mortality rate of the patients..." The doctor who gave the report then pointed to the pictures in front of him, and said: "These are the patients I received. The age ranges from 1 to 18 years old, and most of them are heavy, with abdominal swelling like a drum and deformed head..."

"The premature death rate of thalassemia is very high, because it is the cause of genetic disease, severe patients often die before the age of 15 to 20, the average age in our country is lower, expensive treatment costs are on the one hand, and there is a shortage of medicines On the other hand..."

"The main cause of premature death in patients with thalassemia is the side effect of iron accumulation, because the body cannot produce enough hemoglobin and red blood cells, and patients often need blood transfusions. The resulting iron accumulation will affect the human body. The functions of various organs are seriously affected. Clinically, we need to use iron chelating drugs to remove iron. At present, the most commonly used and only iron chelating agent we can use is deferoxamine, which was first used clinically in 1963. It has caused an upsurge in the research of iron chelators in the medical field, but unfortunately, until today, there are still no new drugs..."

"Nevertheless, we have been able to dig into the potential of deferoxamine by doing research on, that is, the different clinical manifestations of deferoxamine. For example, the microinjection pump administration currently in use can improve drug distribution and accelerate iron deficiency. Shifting metabolism... Through the above methods, we have been able to extend the average life expectancy of patients by about two years..."

After the doctor finished his report, he didn't receive much applause. Although his preparation was much richer than others, the result was not satisfactory.

Although clinically speaking, prolonging the average life expectancy of patients by two years is already a victory, but in the face of patients who die prematurely under the age of 20, such a victory is really humble.

Yang Rui twisted his body uneasily, and said, "Thalassemia is thalassemia."

"Yes, it's also called thalassemia." Wang Sisheng understood the relevant content and answered with understanding.

Yang Rui said: "In 1982, the year before last, when we were researching hydroxypyridone compounds, didn't we discover a new iron chelator, deferiprone? Didn't it become a medicine?"

"Thalassemia is a genetic disease. The main patients are in Southeast Asia, and there are also some black people in Africa. European and American pharmaceutical companies are too late to make cephalosporins. How can they be willing to invest in this area?" Wang Sisheng shook his head lightly, saying hopelessly : "The total number of patients with thalassemia is not many, and deferoxamine is being used..."

"Severely ill patients can't even live to be 20 years old. Of course there are not many of them." Yang Rui curled his lips, silent on the surface, but extremely uncomfortable in his heart.

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