Rebirth of the God-level Xueba

"Genomics illuminates the way for the brave and is changing the ecology of the field of genetics. The timid may fear genomics today, just as they feared genetics back then, but, gentlemen and ladies, genomics Science has taken a step forward, we either follow it, or we can only look at it from afar..." Linden's explanation is simple and vivid, which has the flavor of American movies in the 1970s.

To the Chinese, this way of speaking is both familiar and American, and they couldn't help applauding.

Applause for friends from the United States, everyone worked hard.

Director Ma also applauded vigorously, especially after Yang Rui stepped onto the stage.

"Thank you, Mr. Linden." Yang Rui took the microphone, smiled, and said, "Thank you for the invitation from Norton Publishing House, allowing us to gather together today, because it is a gathering organized by a publishing house from the United States. Rules, let’s not invite the leaders to speak..."

There was a burst of laughter from below. For the current Chinese people, especially civil servants and officials, the level of such jokes is very deep.

Yang Rui smiled again, grabbed the "Genomics" on the small podium, showed it to everyone, and said, "I want to talk about genomics, or more precisely, the development of genomics. As we all know, modern genetics The research focus of science and biology is related to structure, that is to say, what we want and need to know at present is the structure, the structure of genes, the structure of proteins, and the structure of cells. "The most frequently read articles are current hot spots, but..."

"Prospectively speaking, structure should not be our focus. Of course, we still need to study structure, but research on structure should not be the focus, nor should it be a hot spot..."

"What are the key points and hot spots? In my opinion, it should be the function. Don't fall in love with treacherous ministers!"

"Functional genomes, functional proteins, and functional cells are our goals, focus, and hotspots. This is also the main reason why I wrote "Genomics"..." Yang Rui started the topic very high, with deep eyes.

He had reason to prove it with deep eyes, because the speech he was giving was indeed important.

Yang Rui is predicting the arrival of the post-genome era. The genome here refers to the Human Genome Project, which means the biology after the Human Genome Project.

However, if the post-genome era of the Human Genome Project is replaced by the post-genome era after "Genomics", it seems that there is no big problem.

The crux of the problem lies in the fact that the functional genome replaces the structural genome.

Genomics was originally a theoretical guide to the Human Genome Project.

In short, "Genomics" is equivalent to architectural design, while the Human Genome Project is actually engineering construction.

Yang Rui naturally wanted to take this opportunity to make more faces.

The prediction of no money may not mean much to ordinary people, but it is of great value in the scientific community.

Yang Rui has done this kind of thing before, and it is also very rewarding.

So, he couldn't help but prepare to do it again.

Just as astronomers predict black holes, biologists can be as famous for predicting the post-genome era as they are successful.

Yang Rui hopes that his "Genomics" will be able to take advantage of the post-genome prophecy to soar into the sky.

At that time, when people talk about the post-genome era, they will naturally mention Yang Rui's "Genomics".

It is even possible to call "Genomics" the theoretical guidance of the entire post-genome era.

The so-called big bull who can't get around is standing up step by step like a technical barrier. You have to stack one brick on top of another and put cement in the middle, so that it will be more stable.

Just like Newton, if you only get Newton-Leibniz equation, although this brick is very strong and tight enough, it is enough for Newton and Leibniz to be called the darling of the times, but it is not Newton after all, but if you With the addition of the algebraic brick of integrals, it will be different. This is an important step in turning mathematics from a sensory subject to a thinking subject, and it is the founder of the real natural science.

Of course, if only this is the case, Newton is still not Newton, even if he adds analytic geometry and polar coordinates, plus "Cubic Curve" and "Generalized Arithmetic", he is not the Newton in people's impression, but can only be said to be a The great mathematician is on a par with the little prince Gauss and the great emperor Euler.

And the reason why Newton is Newton is that in the big wall he built, there are Newtonian mechanics composed of Newton's three laws, the law of gravitation, the law of planets, and the law of optics... So, in the end, he kept pace with him. It's Einstein...

"Genomics" is Yang Rui's first book, and it is a very representative big brick. Yang Rui spent a lot of thought on this, and also extended the speech to fifteen minutes.

Of course, in terms of domestic speeches, this is nothing.

It was a pity that no more than a quarter of the people present could understand what he was saying.

But Yang Rui doesn't care, this speech is not just for the audience, just like the speech at the secretary's office meeting is not just for chatting with other people in the meeting, or the report at an academic report meeting is not just for the audience. It's not just being cold and authoritarian like the scholars present (wangwang).

The post-genome era will not be realized today, nor will it be realized tomorrow, but one day in the future, when the era of functional genome research gradually replacing structural genome really comes, today's speech will become very meaningful .

Just as patents were not meant to be valid at that time, patent barriers are not meant to keep out today's patent thieves.

However, scholars who could understand, mainly those from invited universities and research institutes, still listened quite seriously.

The concept of the post-genome era is actually very simple. In layman's terms, it is to replace structure with function.

The so-called functional genome is to examine the function of a genome, for example, the existence of the leg-shaking gene, its function is to shake the legs, if the m-shaking gene exists, its function is to shake the m, as for its structure, in terms of biology, although It still has great meaning, but from a more macro perspective, the meaning is not as great as the function.

In the final analysis, as Yang Rui said, it is a question of who is more important. It's not that the structure is not important, but the function is more important.

In the past few years, people did not have the conditions to do functional genomes, so people are more concerned with structural genomes. However, with genomics and the Human Genome Project, structural genomes should give way to functional genomes up.

A quarter of an hour later, Yang Rui's speech ended, and someone below immediately raised their hands.

"This...we're not holding an academic report." Linden from Norton Publishing stood up and smiled, "We didn't prepare for the defense."

"Just one question." The man who raised his hand was an academic man in his 30s wearing glasses.

Lin Deng hesitated, and said, "Just one question, please ask."

"I would like to say that we must first understand the structure before we can understand the function. Moreover, there is another advantage of studying the structure first. We can use the same or similar structure to know the unknown function of an unfamiliar structure..."

"I prefer to call what you said comparative functional genomics." Yang Rui shrugged and said, "On the basis of genome map and sequence determination, we compare known genes and genome structures to understand gene functions. and expression mechanism, which will be the focus of development in the next few years, but what I want to say is the ultimate direction, our ultimate goal, is to use the information provided by structural genomics to develop and apply experimental methods, at the system level, Study the function of the genome, thereby expanding the research object from the study of a single gene and protein to the joint action of multiple genes and proteins..."

The academic man wearing glasses tilted his head and said, "Your end is too far away. How many years will it take, 50 years, 100 years?"

"How about 15 years." Yang Rui said: "At most 25 years, we will fully enter the era of functional genomics."

"How is it possible." The academic man with glasses smiled: "We need to do structural genomics first, all the genes and proteins, how many years will it take? Even if we only complete 50%, or 30%, 50 years will not be enough..."

"It is not necessary to complete the structure of all genes and proteins, and 30% is not necessary. In fact, the Human Genome Project should be launched immediately. Fifteen years is enough for us to understand the structure of genes." Yang Rui smiled, Put down the microphone and gesture to Linden.

Lin Deng immediately stepped onto the stage, ended the topic, and said with a smile, "Now, please welcome our guests..."

The boring leader's speech began here, and the academic man with glasses couldn't ask any more questions.

Director Ma waited for Yang Rui to sit on the chair, and said with a smile: "The one who asked the question just now seems not convinced yet."

Yang Rui glanced back, the academic man with glasses was really full of words, he didn't seem to have said enough, if the scene wasn't serious, he might have run over now, or simply stood up and yelled bone debt.

"There is nothing you can do if you are not convinced." Yang Rui smiled and said, "I didn't tell him."

"how to say?"

"This is a prophecy. For things like prophecy, it is always debated before it is realized. I don't think it is necessary." Yang Rui said simply.

"I don't bother to explain." Director Ma saw through it at a glance, he was too familiar with Yang Rui's expression.

Yang Rui didn't explain, but still smiled lightly.

"Speaking of which, Xiao Yang, it's fine for me to call you that, what does your family do." Director Ma looked like a good old man.

"Oh, my father used to be the secretary of the township party committee, but now he's transferred to the China Merchants Bureau." Yang Rui didn't hide anything, it was all public information.

Director Ma nodded "Oh" and said with a smile, "China Merchants Bureau? It's the same system as the Commercial Bureau. I'm quite familiar with this area."

"Aren't you from the Ministry of Education?"

"I get to know each other when we meet often. You know, ministries and commissions often have to sign something. I often go to the Ministry of Commerce to sign." Inter-departmental cooperation often requires leaders of different departments to sign, which is called counter-signature, and running a sign is a reminder. signed. The division chiefs of central ministries and commissions have great powers and responsibilities, which is also related to this.

Yang Rui said casually, "Do the Ministry of Education and the Ministry of Commerce still communicate frequently?"

"Nowadays, who doesn't want to associate with the Ministry of Commerce." Director Ma laughed, and said, "Fortunately, I'm in the Ministry of Education. If it's the Education Bureau, I'm really embarrassed to go to the Ministry of Commerce."

At this point, Director Ma paused and said again: "Speaking of which, I do have a few friends in the Ministry of Commerce who are also high-level intellectuals. Maybe you have something to chat with. I will make an appointment someday to chat with you." chat."

"Okay." Yang Rui said casually.

Director Ma didn't notice it this time, he just felt that he was almost ready, so he gestured to the back with his eyes.

The man who had been whispering to Director Ma before immediately stood up and said with a smile, "Yang Rui, you are lucky. Director Ma likes to promote young people the most."

"Thank you Director Ma." What can Yang Rui say, but he can't say, I don't need your promotion.

The man sitting on the right side of Director Ma came over to the **** with a bearded smile and said, "Yang Rui, you can't be shy at this time, do you know what Director Ma is in charge of in the department? "

"What do you care?"

"Let's not talk about anything else, the review of university textbooks is under the control of Director Ma." The charming man with a beard rested his chin on his hand and winked at Yang Rui.

Yang Rui was stunned. He really didn't expect that the person next to him could actually promote him. It can only be said that the responsibilities of the Chinese government are so comprehensive.

"If your book can be included in the designated textbooks of the university, that is, the catalog of reference books, it will sell a lot more." The charming man continued to increase his price.

Yang Rui nodded. Not only can it sell a lot more, there are so many colleges and universities in China, if it can be included in the teaching materials, the purchase volume of the library alone can explode the sales in the United States, every student has a copy, and the cheap price can make The publishing house and the author have made a lot of money. It is no wonder that Director Ma was invited by Norton Publishing House to participate in today's publishing briefing and sit next to him.

"Director Ma, please give me your advice." The county magistrate is not as good as he is now, and Yang Rui's smile is much more sincere.

"Okay, okay, I like to teach young people the most. Let's have a good chat someday when we are free." Director Ma said and handed Yang Rui a business card, asking Yang Rui to find him, which is naturally more imposing than him looking for Yang Rui.

...