Into Unscientific

After sorting out his thoughts, Xu Yun returned to the bookshelf again and found the books he needed again.

But what was different from before was that the two girls who had talked about Professor Lu and were suspected of majoring in physics had disappeared, and it was unclear whether they could find the Newton materials they wanted.

At this moment, Xu Yun somewhat realized that his previous behavior was indeed a little weird. Fortunately, the University of Science and Technology has a clear and clear school spirit, and in some schools, he would have to be smeared before he finished speaking.

Then Xu Yun shook his head, put these things aside, and spent half an hour finding three books and several periodicals.

After completing the borrowing and follow-up, I returned to my little nest.

As mentioned earlier, there are nine subtypes of sodium channels in mammals, namely NaV1.1-NaV1.9.

At present, there are six subtypes that are more in-depth in biological research, and the typical representatives of technology application are some class I antiarrhythmic drugs.

For example, quinidine, lidocaine, and propafenone all work by blocking sodium channels.

Another example is that when you are accidentally bitten by spiders, poisonous snakes, scorpions, and succubi, the toxins also act on sodium ion channels and cause adverse consequences.

As for the sodium channel of insects?

The situation is more complicated.

In fact, insects have only one or two voltage-gated sodium channel α subunit genes, but two post-transcriptional modifications—that is, alternative splicing and RNA editing—result in the functional diversity of insect sodium channels.

In addition, the β auxiliary subunits TipE and TEH1-4 of insects also play an important role in the expression and regulation of sodium ion channels.

Therefore, the binding formula that Xu Yun needs to deduce is not simply assembling proteins, but the binding speed of specific receptors is the most important thing.

This is like the little blue pill, the onset of effect in two hundred minutes and the onset of effect in two minutes are completely different concepts.

In more detail, it is necessary to consider the crystal structure and modeling of NDT-A.

At present, many teams in the biological world are researching on the sodium channels of insects, but the results are generally not obvious, and it is difficult to form a complete chain of modules.

However, this just gave Xu Yun a chance to refer to materials from multiple angles. The more important point is that

He still has a trump card that is useless.

At this moment, Xu Yun was sitting in front of the desk, holding a small black card and gently turning it in his hand.

The card is about the same size as a bank card, and has an alloy texture throughout. There is a calf's head portrait painted on it, with sharp eyes and confident flamboyance.

That's right.

This is one of the rewards for the novice task, the 30-minute Mavericks please God is wrong, experience card!

According to Xu Yun's induction, as long as he activates this card's dark thoughts, he can have the thinking ability of Mavericks at the age of 22, which lasts for 30 minutes.

The ability of the 22-year-old Mavericks has been briefly mentioned before, so I won't repeat it here.

"Tsk, it's a pity that it's only half an hour, which is still a bit short."

Xu Yun rubbed his temples with some headaches, picked up a pen and paper, and made arrangements:

"The expression of TipE must not consume the experience card. It is better to use or not to use the action potential conduction of neurons in the peripheral nervous system. After all, there are many related papers."

"The combination point must be used, there are more than two thousand Hehezi."

Xu Yun wrote and drew like this, and after careful consideration, it took a full hour to determine several nodes:

First, the expression of TipE, the open conformational structure and the derivation of the adjacent subunits of the β1-β2 chain were independently completed by ourselves.

Secondly, the combination of the sodium ion channel and the binding site of imidacloprid and the cytoplasmic region is handed over to the calf.

The final combined review will be completed by yourself.

After confirming these steps, Xu Yun immediately began to calculate.

At present, most of the papers on insect sodium ion channels have been submitted to the "Annual Review of Entomology", so among the materials brought back by Xu Yun, four of them are serials of the "Annual Review of Entomology".

And it is a coincidence that TIPE2 is a new immune checkpoint molecule of NK cells, and Tian Liangwei happens to be an expert in NK cells, so the first problem is not particularly difficult to solve, but no one has abducted the decoy protein there. .

Just like online novels, Chendong and Fenghuo have unique styles, and it is difficult to imitate even if you try to imitate them, but it’s not that no one wrote them at the beginning, but that no one thought of these directions.

Once someone discovers this kind of subject matter, there will be a lot of followers on the recommendation position every minute, and the reason is the same.

Soon, Xu Yun locked on one of the more authoritative papers:

"DOI: 10.33086/jhs.v10i2.136 Well, the author is still a senior who has graduated for a long time? Associate Professor at Stanford

The potential difference between the receptor subtypes of Lygus grazing bugs is 2.345, and that of Periplaneta americana is 2.344, which is obviously a kind of expression. Very good, that’s all! "

At present, Xu Yun's comprehensive ability is roughly equivalent to that of an associate professor at HKUST, that is, above the sub-high level, barely equal to the full-time high of a partial subject, but still some distance away from the full-time high of a mainstream subject.

There are quite a few 30-year-old high-ranking monsters in China, so Xu Yun’s original goal was to strive for the title of 28-year-old Shanghai University of Science and Technology, which is almost the way of Academician Cao Xuetao of Nankai University.

Of course.

Now, with the gradual manifestation of the effect of the halo, Xu Yun's follow-up trajectory will definitely change, but for now, his ability is still at a quasi-high level, and it is not difficult to independently derive the compound formula with the reference of the paper of.

Then Xu Yun deduced the three items of data of the first node successively through the data in this paper.

"call."

Then Xu Yun took a deep breath, solemnly picked up Mavericks' thinking experience card, and muttered to himself.

"activation!"

call out--

As the command was issued, the experience card instantly turned into a stream of light and escaped into his mind.

Xu Yun's temples felt cold at first, and within a moment, a rather mysterious feeling filled his mind.

how to say

It feels like everything has suddenly become clear.

For example, Xu Yun's eyes inadvertently caught a glimpse of a group of penguins named "Starting Point Seven Boutique Group", and at this time, an author named "The Tenth Small Horn" was sending out a series of mysterious codes.

Xu Yun just scanned it hastily, and wrote down all the numbers in this string of codes:

"magnet:?xt=urn:btih:"

But soon he came back to his senses and turned his attention to the problem in front of him.

At this moment, Xu Yun only thought about the many problems that made him unable to do anything, and came up with many feasible deduction directions.

Although these deduction directions are not as exaggerated as the results can be seen at a glance, some key links have already been solved.

This is the 22-year-old Mavericks, a genius who laid the foundation of modern mathematics in 18 months!

It can even be said that in the next 30 minutes, Xu Yun's thinking ability became the first echelon in the world for a very short time, and it can even be said that it is today.

strongest!

After the initial half-minute adaptation, Xu Yun immediately picked up the pen and paper, and quickly calculated the combination problem.

"The action potential threshold is 130mV, it should be able to reach 133mV"

"There should be axonal depolarization process of binding protein. Well, there are five types. I don't know which kind Lao Qiu and his decoys are connected to. Forget it, let's calculate it together."

"For the point stimulation of IL-12, IL-15 and IL-18, let's use the thesis of the University of Pennsylvania as the deduction base. One of the tenth schools is Professor James Alwine's."

that's all.

Xu Yun browsed and calculated the data at a speed similar to quantum fluctuation speed reading, and the time was slowly passing by every minute.

three minutes.

five minutes.

ten minutes.

twenty minutes

At the twenty-sixth minute, Xu Yun's deduction also reached the most critical moment.

The veins on his forehead were bulging, his breathing was short of breath, he adjusted his posture, and launched a final sprint like the unlocked breach.

Three minutes later, the last few seconds of the time limit approaching.

I saw Xu Yunchang exhaled a breath of foul air, and wrote down a cell section heavily on the paper:

MC38.

Then he threw away the pen, and a sense of fatigue that he had never experienced before surged up:

"good guy"

"finally."

"It's done!"