Into Unscientific

University of Science and Technology of China.

Life Medicine Building.

Four floors of medicinal chemistry laboratories.

Click——

With the sound of the door opening, Xu Yun hurried in from outside the house in a lab coat:

"Old Qiu, what's the matter?"

As a result, before he finished speaking, he noticed the figure of another person in the room:

"Huh? Academician Zhao?"

That's right.

At this time, besides the tool man Qiu Sheng, another old acquaintance of Xu Yun was sitting in the laboratory:

Academician Zhao Zhengguo!

That is, the director of the Experimental Physics Center of the Institute of High Energy Physics, Chinese Academy of Sciences, and the person in charge who led the experiment on the Λ hyperon.

He and Pan Shuai captured a brand new Λ hyperon by relying on the particle orbit calculated by Xu Yun.

"Well, Xiao Xu, good afternoon."

Zhao Zhengguo greeted Xu Yun, pointed at Qiu Sheng with a smile, and explained:

"I want to talk to you about something today. When I first came to see you, Xiao Qiu said that you will be there soon, so I will stay here for now."

"But I'm not in a hurry. The two of you can deal with your affairs first. Do you mind if I stay here and listen?"

Xu Yun admired Zhao Zhengguo's character very much, so he quickly waved his hands:

"I don't mind, of course I don't mind—and besides, how many people in China dare to kick you out?"

After praising Zhao Zhengguo a little, Xu Yun turned his attention to Qiu Sheng again:

"Old Qiu, what's the matter with you?"

Qiu Sheng glanced at Zhao Zhengguo who was sitting quietly listening, and waved at Xu Yun:

"Come and see."

Xu Yun hummed and walked over quickly.

At this time, there was a stack of thick paper reports on the table in front of Qiu Sheng. After Xu Yun approached, Qiu Sheng handed him some pages:

"Here, this."

Xu Yun took it and looked it up on the spot:

"The rotting rate of the Yian bacteria strain and the CCK-8 test report?"

Students who were bacteria in their previous life should know it.

There are many methods for laboratory bacterial activity detection, but generally only a few are commonly used.

For example, chemiluminescence, that is, ATP luminescence.

Adenosine triphosphate is formed by connecting adenine, ribose and three phosphate groups. It releases more energy when hydrolyzed, and is the most direct energy source in organisms.

The exogenous firefly luciferin or luciferase will oxidize the ATP in the cell to generate photons.

Therefore, the ATP content can be detected by monitoring the luminosity, so as to analyze the cell activity and proliferation.

In addition to the ATP luminescence method.

CCK-8 is also a common and efficient detection method.

Its main component is water-soluble tetrazolium salt SST-8 (2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfobenzene )-2H-tetrazole monosodium salt), is a compound similar to MTT.

In the presence of electron coupling reagents.

It can be reduced by some dehydrogenases in mitochondria to produce orange-yellow water-soluble formazan.

The formazan produced after SST-8 is bioreduced by intracellular dehydrogenase can be directly dissolved in the medium, and the more the cells proliferate, the faster the color will be.

"Phosphatidylserine is mainly distributed in the inner layer of the plasma membrane without asymmetric changes."

"Reduction potential value shifted by +228 mV"

"The spectrophotometer readings were 0.434, 0.437, 0.432"

Xu Yun read it line by line, and the numbers made him a little happy.

When he discovered Yi'an Bacteria, Tian Liangwei generously sent Xu Yun a Micro-Matrix and a 350RPM orbital shaker.

Although Tian Liangwei's purpose is not "very pure", part of the reason is to let Xu Yun and others be a guinea pig for microfluidic interface nanoliter injection technology and high polymer feeding method.

However, the improvement in precision brought by these two devices to the laboratory is also visible to the naked eye.

A few minutes later.

Xu Yun raised his head slowly, rubbed his thumb against the report paper, and asked Qiu Sheng:

"Old Qiu, according to the test results, the activity of Yi'an Bacteria is much higher than that of other strains of the Arthrobush genus?"

Qiu Sheng nodded heavily, picked up a can of yogurt from the table and took a sip:

"That's right, according to experiments, the reproduction efficiency of Yi'an Bacteria is extremely high."

"Under a certain density, the only thing that limits their reproduction is the breeding environment of the pentose phosphate pathway product, or in a sense, the number of native donkey hairs."

"in addition."

"Old Xu, the activity of Yi'an Bacteria is not simply higher than that of other Arthrobush species."

Xu Yun frowned and glanced at him, then curled up the experiment report and hit Qiu Sheng on the head:

"This is not the end of the chapter. Why are you pretending to be a riddle? Talk to people!"

"I'm just learning from you. Hey, don't hit me, don't hit me!"

Qiu Sheng rubbed the back of his head, and pointed at the report in Xu Yun's hand with his chin:

"Old Xu, do you still remember the way Yi'an bacteria kills Neisseria and anaerobic streptococci?"

Xu Yun nodded, and answered simply:

"Of course I remember, the bald head attacks."

Neisseria and anaerobic streptococci are bacteria that are abundant in human saliva, and they are also two of the important 'members' that cause bad breath.

Yian Bacteria has an extremely efficient killing ability against these two types of bacteria, and its main method is to split the mycelium, and the mycelium will 'bind' the target bacteria.

This attack method is like a person constantly taking off his hair to kill the enemy, so Xu Yun and Qiu Sheng jokingly called it a hair loss attack.

in the lab.

Seeing that Xu Yun still didn't understand what he meant, Xu Yun had no choice but to mention it again:

"Old Xu, haven't you thought of it yet?"

"The moment Yi'an Bacteria emits mycelium, it is a kind of energy transformation, that is to say, it will emit"

"Electrons! And a lot of them!"

electronic.

When these two light words were passed from Qiu Sheng's mouth to Xu Yun's mind, they suddenly turned into a thunder!

In the blink of an eye.

A tingling sensation suddenly rose from Xu Yun's tailbone and went straight into his mind!

More than ten seconds passed.

Xu Yuncai slowly came back to his senses, looked at Qiu Sheng in a daze, and asked:

"You mean"

"Yi'an Bacteria, can it be used as a power-generating strain for microbial batteries?!"

Qiu Sheng chuckled, apparently very satisfied with Xu Yun's astonishment, and did not remember that when he saw the results of the experiment, his heart was even more shocked than Xu Yun at this time:

"Congratulations, the answer is correct, Azkabanga ten points!"

Xu Yun directly ignored the work of this tool man, and at this moment, his mind was completely on Yi Anjun.

There is an old saying in China, which is called awakening the dreamer with one word.

Today's Xu Yun was completely shocked by Qiu Sheng's words, quickly connected the cause and effect together, and formed the general context of the incident in his heart:

a month ago.

After returning to reality.

Xu Yun once organized a brainstorm and mentioned the matter of microbial batteries and hemostatic gelatin with Qiu Sheng, Zhou Shan and others.

Especially for microbial batteries, this project was directly established by Xu Yun as the goal of the next stage.

After all, this is the technology with the thinnest barriers among all rewards. It is so thin that if you directly propose an idea, it will not surprise others at all.

Because the concept of microbial batteries has been around for many years, the whole technology is actually very clear at the theoretical level, and there are only two barriers that are the most difficult:

Power supply strains and current collection methods.

And right now, according to what Qiu Sheng said.

Yi'an Bacteria seems to be a perfect fit for this requirement?

think carefully

Seems reasonable too?

The area where Yi'an Bacteria was discovered was the sewer with the largest flow in the University of Science and Technology, surrounded by Nanako's lair, with millions of cockroaches.

Yi'an Bacteria can clean a piece of pure land in that area, which shows that its biological attributes must have two characteristics:

First.

Can survive in harsh environment.

This harsh condition can be a sewer, but it can also be

Storage tank for microbial batteries.

second.

It must be very efficient at cleaning.

Otherwise, the next round of sewage will come again before the first round is cleaned up, and it is impossible to form the "pure land" that Xu Yun saw at the beginning.

to some extent.

This is also a kind of life evolution by natural selection.

On this basis.

When Yi'an Bacteria starts to engulf other bacteria, the whole process needs to consume, or convert a lot of energy.

The phagocytosis of the hair structure generates an action potential.

According to Qiu Sheng's test results.

The electrical activity of Yian bacteria is very powerful and efficient, even far surpassing Shewanella, the mainstream strain of microbial battery experiments.

Of course.

The rightness of Yi'an bacteria does not mean that the microbial battery of Yi'an bacteria can be produced immediately.

There are still many links in front of Xu Yun that need to be considered or breakthroughs.

For example, how to provide energy for Yian bacteria?

You can't let the user spit directly into the storage slot, can you?

Not to mention how much electricity can be generated by a mouthful of saliva, this kind of behavior is quite disgusting

Perhaps some outdoor enthusiasts can accept this, but it is obviously impossible for Xu Yun to only take care of this group - if small microbial batteries can be released, the audience of business travellers, students, etc. is much larger than the circle of outdoor enthusiasts.

In addition, how to collect electrons is also a technical barrier. It can only be said that it is easier than the most difficult bacteria selection.

Just like this.

The collection of donkey hair will increase again.

Then Xu Yun put away the report and asked Qiu Sheng again:

"I see, Lao Qiu, is there anything else?"

Xu Yun's words were just a casual question, but Qiu Sheng actually nodded his head:

"Well, there is one more thing, which is also related to the biotechnology you mentioned earlier-do you remember the hemostatic gelatin you mentioned?"

Xu Yun was slightly taken aback:

"Of course I remember, why, you have also made progress in the hemostatic gelatin?"

"Strictly speaking, progress is not considered."

Qiu Sheng shook his head and explained:

"It was just in the course of my research that I found a material direction that seemed feasible."

Xu Yun frowned even more upon hearing this:

"The research process? I remember that we haven't established a project on blood coagulation gelatin, have we?"

Xu Yun's remarks are naturally not questioning Qiu Sheng's private tricks. The relationship between him and Qiu Sheng for two lifetimes gave him an extraordinary degree of trust in Qiu Sheng.

So what he said was literally:

Hemostatic gelatin was just an idea that Xu Yun mentioned casually during the brainstorming period, and he didn't even do the preliminary demonstration, let alone start the research project.

Therefore, there must be no relevant equipment and materials in the laboratory at present, how can Qiu Sheng produce results out of thin air?

Seeing Xu Yun's bewildered expression, Qiu Sheng opened the drawer and took out a test tube.

I saw in the test tube, impressively placed

Another tuft of donkey hair.

Then Qiu Sheng shook the test tube a few times and explained:

"Old Xu, haven't I been doing the amplification of Yi'an Bacteria all this time? I used a lot of donkey hair as the culture medium."

"Since we want to screen for the most suitable culture medium, it is natural to add some other substances as a control group to optimize the most suitable amplification environment, right?"

Xu Yun nodded, and Qiu Sheng's words are not difficult to understand:

"Exactly.

Then Qiu Sheng continued:

"As a result, when I was doing quantification, I suddenly found that a tuft of donkey hair was stained with some mucus. After standing with benzoquinoline for a period of time, the mucus would form a very high-viscosity colloidal object."

"So I thought of the coagulated gelatin you mentioned, and tried a rheometer to measure the longitudinal adhesion of that substance, and the result."

"Its viscosity curve exceeds 860! It is more than six times that of 502 glue!"